Obesity is associated with chronic low-level inflammation, which can promote cancer development. Weight loss can reduce inflammation in the body, potentially lowering the risk of cancer.
Excess body fat, especially around the abdomen, can lead to higher levels of certain hormones like insulin and estrogen.
Obesity is often associated with insulin resistance, which can lead to higher insulin levels in the body. High insulin levels have been linked to an increased risk of some cancers.
Adipose tissue (fat cells) can release hormones and cytokines that promote inflammation and cell proliferation, both of which can contribute to cancer development.
Weight loss has been particularly effective in reducing the risk of certain obesity-related cancers, such as breast, endometrial, colorectal, and kidney cancers.